A Case of Mistaken Identity: Are Reactive Oxygen Species Actually Reactive Sulfide Species?
نویسندگان
چکیده
منابع مشابه
A case of mistaken identity: are reactive oxygen species actually reactive sulfide species?
Stepwise one-electron reduction of oxygen to water produces reactive oxygen species (ROS) that are chemically and biochemically similar to reactive sulfide species (RSS) derived from one-electron oxidations of hydrogen sulfide to elemental sulfur. Both ROS and RSS are endogenously generated and signal via protein thiols. Given the similarities between ROS and RSS, we wondered whether extant met...
متن کاملMeasuring redox-active species in cells and tissues. Focus on "A case of mistaken identity: are reactive oxygen species actually reactive sulfide species?".
THE GENERATION OF REACTIVE oxygen species (ROS) is inevitable for aerobic organisms and generally occurs at a controlled rate, with endogenous mechanisms tightly regulating ROS production and metabolism. Alterations in the balance between oxidant production and metabolism can lead to enhanced oxidative stress, which promotes oxidative damage to a wide range of biomolecules. The accumulation of ...
متن کاملO 22: Reactive Oxygen Species and Epilepsy
Seizure activity has been proposed to result in the generation of reactive oxygen species (ROS), which then contribute to seizure-induced neuronal damage and eventually cell death. Although the mechanisms of seizure-induced ROS generation are unclear, mitochondria and cellular calcium overload have been proposed to have a crucial role. We aim to determine the sources of seizure-induced ROS and ...
متن کاملI-3: Reactive Oxygen Species: A Dilemma for
Spermatozoa are very special cells and constantly exposed to the interphase between oxidative stress through high amounts of reactive oxygen species (ROS) and leukocytes, and reduction by means of scavengers and antioxidants. Considering the very special functions of spermatozoa as being the only cells with such high polarization and exerting their functions outside the body, even in a differen...
متن کاملReactive oxygen species are indispensable in ovulation.
Ovulation is stimulated by the preovulatory surge of the pituitary luteinizing hormone (LH). Because the ovulatory response is commonly identified with inflammation, we explored the involvement of reactive oxygen species (ROS) in this process. Our experiments show that administration of broad-range scavengers of oxidative species into the ovarian bursa of mice, hormonally induced to ovulate, si...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2016
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.30.1_supplement.742.13